Since the insulin gets to the liver through the portal vein within the oral check, we feel that it additional closely approximates physiological condi¬tions. It is not too vital, but, which check is used, provided the investigator confines himself to 1 procedure which will provide him results from which he can draw compari¬sons. The three-hour intravenous check gives regarding the same results as the slower oral check, if we compare proportionate fractions of the check period. Dr. Portis tested nine hundred and twenty-nine patients. Their blood sugar levels were determined within the fasting state and then one-0.5, one, two, and three hours when fifty grams of glucose resolution were injected. “In not one of these nine hundred and twenty-nine patients did the third-hour level reach the initial fasting level. The Assyrians and also the Greeks used propolis to assist maintain sensible health. Containing 22 amino acids, B-advanced vitamins and fortified with royal jelly, Bee Propolis is a wonderful means to assist support the body’s natural defenses. In the one hundred and fifty-seven persons of the fatigue cluster, as distinct from the seven hundred and seventy-two having alternative than fatigue symptoms, the reading for the first thirty minutes was thus low that the curves were ‘flat’ compared with the curves of each traditional persons and persons while not fatigue as predomi¬nating symptoms.” These fatigue patients differ from alternative hyperinsulinism patients each in their symptoms and within the larger “flatness” of the curves derived from their Glucose Tolerance Tests.

Fatigue, and not hunger, is the predominating symptom. Though a number of the fatigue patients also had weakness, tremulousness, sweating, vertigo, and lightheadedness as pre¬viously noted, solely a terribly few had apprehension. One, a physi¬cian, had developed phobias. A twenty-year-old boy who had all-time low fasting blood sugar level, the “flattest” curve, and therefore the lowest third-hour reading—all below sixty mg. per cent (anything below 70 mg. is subnormal)—exhibited extreme shyness, might not concentrate, and showed definite schizoid tendencies. (Statistics indicate that low blood sugar is char¬acteristic of schizophrenia.) Dr. Portis believes that this larger “flatness” of the fatigue curves is because of the stimulus of the proper vagus nerve affect¬ing the insulin secretion of the islands of Langerhans to such an extent that the usual initial rise in blood sugar is checked. With this in mind, the following check was made with fifteen of the first fifty-5 fatigue patients.

”A sample of the fasting blood was taken. Royal Jelly could be a milky secretion derived from the pharyngeal glands of the honey bee. The patient was then given 1/fifty grain [1.three mg.] of atropine sulfate hypodermically. Once a 0.5 hour for adequate pharmacologic action of the drug, another blood sample was withdrawn. Im¬mediately thereafter fifty per cent dextrose was injected as within the previous check, which had given ‘flat’ curves, and blood samples were withdrawn at the usual intervals. In these fif¬teen atropinized patients, the thirty-minute blood sugar level resembled that of traditional persons. Because of the uni¬formity of leads to this cluster, I felt that there was no would like to subject a large cluster to the current test.”